South African-led research has revealed new molecular details about how cancer changes the MUC1 protein to evade the immune system. The findings could support the development of new cancer vaccines, biomarkers and precision therapies. MUC1 is found on epithelial cells lining organs including the breast, colon and lungs. In healthy tissue, it carries long, complex sugar chains that help protect…
Tag: Cancer Immunotherapy
-
Moderna Merck Melanoma Vaccine Shows Late-Stage Success
Moderna and Merck have announced that late-stage trials of a personalised mRNA cancer vaccine for the treatment of melanoma have yielded positive results. The companies stated that the treatment reduced the risk of melanoma recurrence or spread when used in conjunction with Merck’s immunotherapy drug Keytruda. Notably, Keytruda is already widely used to treat melanoma and several other cancers. This…